NCT07894510 Nanohydroxyapatite Versus Sodium Fluoride Varnish in Remineralizing MIH Anterior Teeth
| NCT ID | NCT07894510 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Tanta University |
| Condition | Fluoride Varnishes |
| Study Type | INTERVENTIONAL |
| Enrollment | 26 participants |
| Start Date | 2026-01-03 |
| Primary Completion | 2026-11 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 26 participants in total. It began in 2026-01-03 with a primary completion date of 2026-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled clinical trial evaluates and compares the remineralization efficacy of a 8.6% nanohydroxyapatite (nano-HAp) varnish versus a standard 5% sodium fluoride (NaF) varnish in young permanent anterior teeth affected by Molar Incisor Hypomineralization (MIH).
Eligibility Criteria
Inclusion Criteria: * Child had one or more MIH-affected permanent incisors exhibiting a non-cavitated initial carious lesion on the labial surface. * Lesions with a score of 1 or 2 according to the International Caries Detection and Assessment System (ICDAS). * Healthy children without any systemic disease. Exclusion Criteria: * Severely decayed, fractured, or restored MIH-affected teeth that can't be evaluated for varnish effects. * Presence of orthodontic appliances. * Developmental defects of enamel other than MIH (Amelogenesis imperfecta, dentinogenesis imperfecta, erosion, dental fluorosis). * Uncooperative patient and parent.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07894510 clinical trial?
This trial is open to participants of all sexes, aged 8 Years or older, up to 11 Years, studying Fluoride Varnishes. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07894510 currently recruiting?
Yes, NCT07894510 is actively recruiting participants. Contact the research team at shaimaaeldesouky@dent.tanta.edu.eg for enrollment information.
Where is the NCT07894510 trial being conducted?
This trial is being conducted at Tanta, Egypt.
Who is sponsoring the NCT07894510 clinical trial?
NCT07894510 is sponsored by Tanta University. The trial plans to enroll 26 participants.