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Recruiting NCT05369429

NCT05369429 My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

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Clinical Trial Summary
NCT ID NCT05369429
Status Recruiting
Phase
Sponsor Northwestern University
Condition Cancer
Study Type INTERVENTIONAL
Enrollment 6,516 participants
Start Date 2022-12-02
Primary Completion 2028-07-05

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
My Wellbeing Guide

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 6,516 participants in total. It began in 2022-12-02 with a primary completion date of 2028-07-05.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami Health System. Eligible patients will be directly contacted by the study team for recruitment. The intervention includes cognitive behavioral therapy management strategies for health-related stress in the form of animated videos, interactive activities, and written content. The intervention will be delivered via an online application over an 7-week period. Intervention participants will also complete four assessments: baseline (at the beginning of the research study), post-intervention (7 weeks after baseline), a 6-month follow-up, and a 12-month follow up. Participants are randomized into either an intervention application (described above) or a control application (which will provide links to helpful resources for patients with cancer, such as the contact information for cancer support services at Northwestern University and the University of Miami, and the link to the National Cancer Institute website, and the American Cancer Society website.) Control participants will also complete four assessments: baseline (at the beginning of the research study), post-intervention (7 weeks after baseline), a 6-month follow-up, and a 12-month follow up.

Eligibility Criteria

Inclusion Criteria: a) having been reached out to by the study team for recruitment; (b) planned treatment and follow-up within the NM or UHealth healthcare system; (c) ≥ 18 years of age; (d) medical chart confirmed diagnosis of a solid or hematological malignancy; (e) elevated depressive symptoms on the PROMIS CAT (score \> or = 55) within the last 3 months; (f) access to the internet; (g) willingness to be randomized; (h) able to read English or Spanish; (i) patients must have signed informed consent prior to registration on study Exclusion Criteria: Note: The investigators will not include any vulnerable populations in this study.

Contact & Investigator

Central Contact

Ro Mercer, BS

✉ ro.mercer@northwestern.edu

📞 312-503-3943

Principal Investigator

Betina Yanez, PhD

PRINCIPAL INVESTIGATOR

Northwestern University

Frequently Asked Questions

Who can join the NCT05369429 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05369429 currently recruiting?

Yes, NCT05369429 is actively recruiting participants. Contact the research team at ro.mercer@northwestern.edu for enrollment information.

Where is the NCT05369429 trial being conducted?

This trial is being conducted at Chicago, United States.

Who is sponsoring the NCT05369429 clinical trial?

NCT05369429 is sponsored by Northwestern University. The principal investigator is Betina Yanez, PhD at Northwestern University. The trial plans to enroll 6,516 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology