NCT07502989 Muscle Health Measurements Using Electrical Impedance Myography
| NCT ID | NCT07502989 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Beth Israel Deaconess Medical Center |
| Condition | Myopathy |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2025-04-09 |
| Primary Completion | 2027-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2025-04-09 with a primary completion date of 2027-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is being done to further develop a device, the mScan, to measure muscle health as compared to measurements of muscle health using MRI (magnetic resonance imaging). This device is held against the skin and uses Electrical Impedance Myography (EIM). EIM uses a very small, noninvasive (e.g. no needles), brief (about 6 seconds), and painless electrical current to measure the muscle. The investigators will look at how the mScan predicts the muscle measurements seen on MRI in people with and without muscle disease. The investigators hope that this can be used in the future as a quick, convenient and less time-consuming way than MRI to assess muscle health. This could be used to measure how well treatments for different muscle disorders are working over a period of time.
Eligibility Criteria
Inclusion Criteria: * Ages 18-89 * Evidence of a primary myopathic condition as determined by detailed chart review, including results of genetic testing, serological data, or previous muscle biopsy Exclusion Criteria: * Inability to lie flat or history of claustrophobia * \>1+ lower extremity edema * Presence of multiple other pathologies affecting lower extremity muscles to be studied * Pregnancy * Contraindications for MRI scanning - e.g. MRI incompatible pacemaker, deep brain stimulator, or lower extremity hardware * Contraindications to undergo DXA Scan * Any studies/scans with a radioisotope within the past 15 days * Any imaging with radiographic contrast in the past 7 days * Weight greater than 450 lbs * Calcium supplements or antacids containing calcium in the past 24 hours * Severe obesity with BMI \> 35 kg/m2, given difficulties fitting in MRI scanner and impact of severe obesity on EIM data * Chronic skin conditions with ulcerations which would interfere with EIM electrode contact or be uncomfortable for the participant
Contact & Investigator
Pushpa Narayanaswami, M.D.
PRINCIPAL INVESTIGATOR
Beth Israel Deaconess Medical Center
Frequently Asked Questions
Who can join the NCT07502989 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 89 Years, studying Myopathy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07502989 currently recruiting?
Yes, NCT07502989 is actively recruiting participants. Visit ClinicalTrials.gov or contact Beth Israel Deaconess Medical Center to inquire about joining.
Where is the NCT07502989 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT07502989 clinical trial?
NCT07502989 is sponsored by Beth Israel Deaconess Medical Center. The principal investigator is Pushpa Narayanaswami, M.D. at Beth Israel Deaconess Medical Center. The trial plans to enroll 150 participants.