NCT06261866 Multimodality Imaging and Functional Lesion Assessment in Intermediate Coronary Stenosis in Chronic Coronary Syndrome
| NCT ID | NCT06261866 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Warsaw |
| Condition | Chronic Coronary Syndrome |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2011-04-07 |
| Primary Completion | 2024-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2011-04-07 with a primary completion date of 2024-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this prospective, investigator-initiated study is to evaluate the diagnostic accuracy and correlations between functional indices (fractional flow reserve, FFR) and morphometric indices: luminal and qualitative parameters assessed by optical coherence tomography (OCT) including minimal lumen area, plaque type, presence of thin cap fibroatheroma among patients with chronic coronary syndrome identified with intermediate grade coronary stenosis.
Eligibility Criteria
Inclusion Criteria: * 18 years or older * Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT) * Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography * FFR and OCT examination of the same lesion * The patient is willing to participate in the study and has provided a written informed consent Exclusion Criteria: * Acute coronary syndrome * Proximal left main lesion * Ostial right coronary artery lesion * Bypass of the assessed vessel * Contraindications for adenosine administration * Hemodynamic instability * Heart insufficiency in New York Heart Association (NYHA) class IV scale * Acute renal insufficiency * Pregnancy
Contact & Investigator
Mariusz Tomaniak
✉ mariusz.tomaniak@wum.edu.plMariusz Tomaniak, MD, PhD, Assoc. Prof.
PRINCIPAL INVESTIGATOR
Medical University of Warsaw
Frequently Asked Questions
Who can join the NCT06261866 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Chronic Coronary Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06261866 currently recruiting?
Yes, NCT06261866 is actively recruiting participants. Contact the research team at mariusz.tomaniak@wum.edu.pl for enrollment information.
Where is the NCT06261866 trial being conducted?
This trial is being conducted at Warsaw, Poland.
Who is sponsoring the NCT06261866 clinical trial?
NCT06261866 is sponsored by Medical University of Warsaw. The principal investigator is Mariusz Tomaniak, MD, PhD, Assoc. Prof. at Medical University of Warsaw. The trial plans to enroll 200 participants.