NCT05581680 Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects
| NCT ID | NCT05581680 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Universitaire, Amiens |
| Condition | Electromyography |
| Study Type | INTERVENTIONAL |
| Enrollment | 720 participants |
| Start Date | 2022-10-12 |
| Primary Completion | 2027-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 720 participants in total. It began in 2022-10-12 with a primary completion date of 2027-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials. The proposed treatments are based on surgery, physiotherapy and botulinum toxin injections. However, when recovery is incomplete, acceptance is more difficult, with an impacted quality of life. Thanks to Motion Capture and Electromyography, a quantification of the facial mimicry is now possible with a great precision. In addition with the quantification of the facial mimicry, eye-tracking, wich is widely used in the marketing field, but it also finds medical applications including head and neck lesions and facial palsy in particular, will be used to evaluate the visio of the patients on their pathology in function of the movement quantification measured with MoCap and Electromyography. The aim of this research is to measure in a combined way the action potentials by sEMG and the amplitudes of displacement of the markers in motion capture, for movements determined in a population of patients presenting a facial pathology, in order to compare them with reference values obtained in healthy subjects. In a second step, the aim will be to study if there is a link between the way the patient looks at his pathology and the results of his management (treatment, rehabilitation) which will be quantitatively evaluated thanks to MoCap and sEMG.
Eligibility Criteria
Inclusion Criteria: * Subjects with no known facial pathology (healthy volunteers) OR * Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated * Subject with written informed consent * Subject over 18 years of age * Subject affiliated to a social security scheme Exclusion Criteria: * Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers * Subjects with speech disorders making it impossible to pronounce the sounds \[o\] and \[pu\] * Subject unable to provide written informed consent * Subjects under guardianship, curators or safeguard of justice
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05581680 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Electromyography. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05581680 currently recruiting?
Yes, NCT05581680 is actively recruiting participants. Contact the research team at dakpe.stephanie@chu-amiens.fr for enrollment information.
Where is the NCT05581680 trial being conducted?
This trial is being conducted at Amiens, France.
Who is sponsoring the NCT05581680 clinical trial?
NCT05581680 is sponsored by Centre Hospitalier Universitaire, Amiens. The trial plans to enroll 720 participants.