NCT07359690 Multimodal Analysis of Endomyocardial Biopsies
| NCT ID | NCT07359690 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Essen |
| Condition | Heart Transplantation |
| Study Type | OBSERVATIONAL |
| Enrollment | 216 participants |
| Start Date | 2025-10-27 |
| Primary Completion | 2028-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 216 participants in total. It began in 2025-10-27 with a primary completion date of 2028-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and therapy. The main aim is: -Identification of molecular profiles (e.g., proteome, lipidome, metabolome) and immune signalling profiles that are specifically associated with different myocardial diseases and the post-heart transplantation course. Participants already receiving an endomyocardial biopsy as part of their regular medical care will be enrolled. An additional biopsy sample will be taken for the above mentioned research.
Eligibility Criteria
Inclusion Criteria: * Patients aged \>18 years with a clinical indication for endomyocardial biopsy. * Patients capable of providing informed consent who have signed the consent form for participation in the study. Exclusion Criteria: * Patients without a clinical indication for endomyocardial biopsy (EMB). * Pregnant individuals. * Patients incapable of providing informed consent. * Women of childbearing potential who are not using adequate contraception.
Contact & Investigator
Lars Michel, PD Dr. med.
PRINCIPAL INVESTIGATOR
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, Germany
Frequently Asked Questions
Who can join the NCT07359690 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Heart Transplantation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07359690 currently recruiting?
Yes, NCT07359690 is actively recruiting participants. Contact the research team at lars.michel@uk-essen.de for enrollment information.
Where is the NCT07359690 trial being conducted?
This trial is being conducted at Essen, Germany.
Who is sponsoring the NCT07359690 clinical trial?
NCT07359690 is sponsored by University Hospital, Essen. The principal investigator is Lars Michel, PD Dr. med. at Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center Essen, University Hospital Essen, Germany. The trial plans to enroll 216 participants.