NCT07488091 Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana
| NCT ID | NCT07488091 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Ghana Medical School |
| Condition | Sickle Cell Disease and Pregnancy |
| Study Type | INTERVENTIONAL |
| Enrollment | 198 participants |
| Start Date | 2026-01-22 |
| Primary Completion | 2028-01-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 198 participants in total. It began in 2026-01-22 with a primary completion date of 2028-01-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital. The main question it aims to answer is: In a before-and-after study design, we will test the hypothesis that multidisciplinary care for pregnant women with SCD in a non-academic hospital will result in a 50% relative risk reduction in mortality compared to the mortality rate in pregnant women with SCD in the same hospital before the multidisciplinary care. Participants will be managed using the academic hospital's multidisciplinary sickle cell disease obstetrics protocol adapted for the non-academic hospital
Eligibility Criteria
Inclusion criteria * Pregnant women with a confirmed laboratory diagnosis of sickle cell disease * Pregnancy confirmed by a pelvic ultrasound scan * Pregnancy should be 34 weeks' gestation or less * Pregnant women should be aged 18 - 45 years * Pregnant women should be attendants at the non-academic hospital Exclusion criteria * All pregnant women with sickle cell disease who do not provide informed consent * All pregnant women with sickle cell disease who are referred for management of acute complications and hospital admission * All pregnant women with sickle cell disease who are referred for labor and delivery * All pregnant women with SCD who plan on delivering outside the non-academic hospital and won't be able to adhere to the follow-up procedures during the puerperium (the first six weeks after childbirth)
Frequently Asked Questions
Who can join the NCT07488091 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 45 Years, studying Sickle Cell Disease and Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07488091 currently recruiting?
Yes, NCT07488091 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of Ghana Medical School to inquire about joining.
Where is the NCT07488091 trial being conducted?
This trial is being conducted at Accra, Ghana.
Who is sponsoring the NCT07488091 clinical trial?
NCT07488091 is sponsored by University of Ghana Medical School. The trial plans to enroll 198 participants.
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