NCT05259826 Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity
| NCT ID | NCT05259826 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Erlangen-Nürnberg Medical School |
| Condition | Food Allergy |
| Study Type | INTERVENTIONAL |
| Enrollment | 115 participants |
| Start Date | 2022-02-01 |
| Primary Completion | 2025-01-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 115 participants in total. It began in 2022-02-01 with a primary completion date of 2025-01-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha). These data will be correlated with serum values and disease status. In addition, organoids from duodenal tissue will be isolated and cultured in vitro and stimulated with the major food allergens. The gene and protein expression will be checked to identify relevant biomarkers.
Eligibility Criteria
Inclusion Criteria: * informed consent * patients with suspected food allergy or hypersensitivity * healthy controls with indications for endoscopic diagnostics, e.g. tumour history within the family, exclusion of gastritis Exclusion Criteria: * pregnant person
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05259826 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Food Allergy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05259826 currently recruiting?
Yes, NCT05259826 is actively recruiting participants. Contact the research team at yurdaguel.zopf@uk-erlangen.de for enrollment information.
Where is the NCT05259826 trial being conducted?
This trial is being conducted at Erlangen, Germany.
Who is sponsoring the NCT05259826 clinical trial?
NCT05259826 is sponsored by University of Erlangen-Nürnberg Medical School. The trial plans to enroll 115 participants.