| NCT ID | NCT00051857 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Institutes of Health Clinical Center (CC) |
| Condition | Abnormalities |
| Study Type | OBSERVATIONAL |
| Enrollment | 750 participants |
| Start Date | 2003-03-05 |
| Primary Completion | — |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 750 participants in total. It began in 2003-03-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will use magnetic resonance imaging (MRI) and ultrasound images to study how muscles, tendons, and bones work together to cause motion. The procedure is one of several tools being developed to characterize normal and impaired musculoskeletal function, with the goal of developing improved methods of diagnosis and treatment of movement disorders. Healthy normal volunteers must be age 5 to unlimited, with or without joint impairment, may be eligible for this study. Volunteers with joint impairment may not have serious injury to the joint being studied, previous surgery on the joint being studied, or extreme pain at the joint being studied. MRI uses a strong magnet and radio waves to create images of the inside of the body. The subject lies on a long narrow couch inside a metal cylinder (the scanner) for up to 3 hours while the scanner gathers data. Earplugs are worn to muffle loud noises caused by electrical switching of radiofrequency circuits used in the scanning process. A special pad or tube may be placed over or around the region being scanned to improve the quality of the data. The subject will be asked to repeatedly move a specific joint, such as the knee, for brief periods, usually less than 5 minutes. The subject can communicate via intercom with the person performing the study at all times during the procedure, and may request to stop the study at any time.
Eligibility Criteria
* INCLUSION CRITERIA: Affected Participants: * Must be between the ages of 5-95 years. * Minors \< 18 years of age, they must be capable of providing assent (verbal or written) with parental or legal guardian permissions obtained. * Adults 18 \>= years of age, they must be able to provide informed consent. * Have the presence of a bone, muscle, soft tissue, connective tissue injury, impairment or related muscular skeletal system pathology. * Ability to have an MRI Scan. Healthy Volunteer Participants * Must be between the ages of 5-95 years. * Minors \< 18 years of age, they must be capable of providing assent (verbal or written) with parental or legal guardian permissions obtained. * Adults 18 \>= years of age, they must be able to provide informed consent. * Ability to have an MRI Scan. EXCLUSION CRITERIA: Affected Participants: -For the MR imaging portion of this study, all participants must complete the NIH Diagnostic Radiology screening questionnaire. If any potential contraindication is found, either the volunteer s doctor (with knowledge of the potential contraindication) or the radiology department at the NIH will be contacted to determine if the potential contraindication would exclude them from the specific MR scans being proposed. Healthy Volunteer Participants * Any relevant medical problems * Clinical signs of an impairment in the joint/limb being studied. * Any serious injury to the joint/limb being studied, previous surgery on the joint/limb being studied or extreme pain at the joint/limb being studied. * Neurologic Pathology affecting the muscular skeletal system * For the MR imaging portion of this study, all participants must complete the NIH Diagnostic Radiology screening questionnaire. If any potential contraindication is found, either the volunteer s doctor (with knowledge of the potential contraindication) or the radiology department at the NIH will be contacted to determine if the potential contraindication would exclude them from the specific MR scans being proposed.
Contact & Investigator
Frances T Gavelli, Ph.D.
PRINCIPAL INVESTIGATOR
National Institutes of Health Clinical Center (CC)
Frequently Asked Questions
Who can join the NCT00051857 clinical trial?
This trial is open to participants of all sexes, aged 5 Years or older, up to 95 Years, studying Abnormalities. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT00051857 currently recruiting?
Yes, NCT00051857 is actively recruiting participants. Contact the research team at gavellif@cc.nih.gov for enrollment information.
Where is the NCT00051857 trial being conducted?
This trial is being conducted at Bethesda, United States.
Who is sponsoring the NCT00051857 clinical trial?
NCT00051857 is sponsored by National Institutes of Health Clinical Center (CC). The principal investigator is Frances T Gavelli, Ph.D. at National Institutes of Health Clinical Center (CC). The trial plans to enroll 750 participants.