| NCT ID | NCT06140940 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hôpital le Vinatier |
| Condition | Aphasia |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2024-03-28 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2024-03-28 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The present study aims to characterize and modulate motor imagery abilities in individuals with aphantasia. The investigators will characterize the neurophysiological and physiological underpinnings of mental imagery abilities in participants with aphantasia by investigating several indices of motor imagery abilities and comparing them to participants with typical mental imagery abilities. The investigators will investigate whether non-invasive brain stimulation applied to the primary motor cortex improves mental imagery abilities in participants with aphantasia.
Eligibility Criteria
Inclusion Criteria: * For the aphantasia group only: congenital aphantasia defined as a life-long inability to generate mental imagery (confirmed by a total score of 32 or less on the VVIQ, which is the gold standard questionnaire for aphantasia) * For the no-aphantasia group only: typical mental imagery capacities (confirmed by a total score of more than 32 on the VVIQ) * Covered by public health insurance * Understanding the French language * Signed written informed consent after being informed about the study Exclusion Criteria: * Presence or history of a somatic, neurologic, or mental illness * Actual pain or musculoskeletal disorders at the upper limb * Having a regular musical activity (more than once a week) because of high manual dexterity * Contraindication for noninvasive brain stimulation including the presence of ferromagnetic or magnetic sensitive metal objects implanted in the head or in close proximity (e.g., brain stent, clip, cochlear implants, or stimulator) * Pregnancy (controlled by urine pregnancy test in females without reported contraception) * Active seizure disorder or history of seizures * Participants under curatorship/guardianship
Contact & Investigator
Marine MONDINO, PhD
PRINCIPAL INVESTIGATOR
CH le Vinatier
Frequently Asked Questions
Who can join the NCT06140940 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Aphasia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06140940 currently recruiting?
Yes, NCT06140940 is actively recruiting participants. Contact the research team at lydie.sartelet@ch-le-vinatier.fr for enrollment information.
Where is the NCT06140940 trial being conducted?
This trial is being conducted at Bron, France.
Who is sponsoring the NCT06140940 clinical trial?
NCT06140940 is sponsored by Hôpital le Vinatier. The principal investigator is Marine MONDINO, PhD at CH le Vinatier. The trial plans to enroll 40 participants.