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Recruiting NCT06213272

NCT06213272 Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

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Clinical Trial Summary
NCT ID NCT06213272
Status Recruiting
Phase
Sponsor Kessler Foundation
Condition Stroke
Study Type INTERVENTIONAL
Enrollment 70 participants
Start Date 2024-04-18
Primary Completion 2029-03-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 85 Years
Study Type INTERVENTIONAL
Interventions
Phono-Motor TherapyAerobic Exercise Training (AET)Stretching

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 70 participants in total. It began in 2024-04-18 with a primary completion date of 2029-03-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment. This approach is expected to increase cerebral circulation and help to rebuild and strengthen the damaged phonological neural networks. Through this combinatory approach, the study aims to enhance the reading and language improvements seen with existing treatments.

Eligibility Criteria

Inclusion Criteria: * fluent and literate in English prior to stroke * 1st ever stroke * more than 3 months post-stroke * post-stroke reading deficits, defined as reading aloud accuracy \<83% for single words or \<65% for readable nonwords * living within a 50-mile radius from Kessler Foundation. Exclusion Criteria: * contraindication to MRI * prior neurological disease * developmental learning or reading disability (i.e., developmental dyslexia) * contraindication to exercise * concurrent speech and language therapy

Contact & Investigator

Central Contact

Olga Boukrina, PhD

✉ oboukrina@kesslerfoundation.org

📞 19733243587

Principal Investigator

Olga Boukrina

PRINCIPAL INVESTIGATOR

Kessler Foundation

Frequently Asked Questions

Who can join the NCT06213272 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06213272 currently recruiting?

Yes, NCT06213272 is actively recruiting participants. Contact the research team at oboukrina@kesslerfoundation.org for enrollment information.

Where is the NCT06213272 trial being conducted?

This trial is being conducted at West Orange, United States.

Who is sponsoring the NCT06213272 clinical trial?

NCT06213272 is sponsored by Kessler Foundation. The principal investigator is Olga Boukrina at Kessler Foundation. The trial plans to enroll 70 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology