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Recruiting Phase 3 NCT06033599

NCT06033599 Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement

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Clinical Trial Summary
NCT ID NCT06033599
Status Recruiting
Phase Phase 3
Sponsor Rutgers, The State University of New Jersey
Condition Polysubstance Abuse
Study Type INTERVENTIONAL
Enrollment 420 participants
Start Date 2023-09-05
Primary Completion 2027-06-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
MORE and MI and NRTMORE and No MI and NRTSupport Group and MI and NRT

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 3 trials are large pivotal studies comparing the treatment to current standard of care or placebo. Your participation directly contributes to the evidence needed for regulatory approval.

This trial targets 420 participants in total. It began in 2023-09-05 with a primary completion date of 2027-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to 1) examine barriers and facilitators to implementation of MI and MORE for polysubstance use and evaluate strategies for optimizing training, fidelity, and clinic uptake, and 2) evaluate patient outcomes related to the effectiveness of MORE decreasing opioid, tobacco, and other drug use.

Eligibility Criteria

Inclusion Criteria: * English-speaking * Age ≥18 * Currently on methadone; and 4) currently smoke cigarettes. Exclusion Criteria: * Severe cognitive impairment (score \>23 on Mini Mental Status Exam) or psychosis (positive SCID Psychotic Screen) * Suicidal risk (score ≥7 on Suicidal Behaviors Questionnaire) * Inability to attend or fully participate in intervention sessions or assessments * Previous formal mindfulness training (e.g., MBSR, MBRP) or MORE (from the R21 or R33 * Currently taking smoking cessation pharmacotherapy or participating in smoking cessation counseling * Any contraindications for NRT * Currently or soon planning to be pregnant or breastfeeding.

Contact & Investigator

Central Contact

Nina Cooperman, PsyD

✉ cooperna@rwjms.rutgers.edu

📞 732-235-8569

Principal Investigator

Nina Cooperman, PsyD

PRINCIPAL INVESTIGATOR

Rutgers Robert Wood Johnson Medical School

Frequently Asked Questions

Who can join the NCT06033599 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Polysubstance Abuse. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06033599 trial and what does that mean for participants?

Phase 3 trials are large-scale studies comparing the new treatment to existing standards of care or a placebo. They provide the evidence needed for regulatory approval. This trial targets 420 participants.

Is NCT06033599 currently recruiting?

Yes, NCT06033599 is actively recruiting participants. Contact the research team at cooperna@rwjms.rutgers.edu for enrollment information.

Where is the NCT06033599 trial being conducted?

This trial is being conducted at New Brunswick, United States, Salt Lake City, United States.

Who is sponsoring the NCT06033599 clinical trial?

NCT06033599 is sponsored by Rutgers, The State University of New Jersey. The principal investigator is Nina Cooperman, PsyD at Rutgers Robert Wood Johnson Medical School. The trial plans to enroll 420 participants.

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