NCT07056881 Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa
| NCT ID | NCT07056881 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier de Saint-Denis |
| Condition | Osteomyelitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2025-04-11 |
| Primary Completion | 2026-04-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2025-04-11 with a primary completion date of 2026-04-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study looks at how well one antibiotic (monotherapy) works compared to two antibiotics (combination therapy) in treating bone infections caused by Pseudomonas aeruginosa. It includes 300 adult patients who had this type of infection confirmed by lab tests and medical imaging. The goal is to find out if using just one antibiotic is as effective as using two, while also looking at side effects, the need for more surgery, antibiotic resistance, and overall antibiotic use.
Eligibility Criteria
Inclusion Criteria: * Adult patients (≥18 years old) * Diagnosis of osteitis or osteomyelitis due to Pseudomonas aeruginosa * Isolation of Pseudomonas aeruginosa from at least one deep, sterile sample (e.g., bone biopsy, joint aspiration) * Imaging findings consistent with osteomyelitis (MRI, CT scan, or X-ray) Exclusion Criteria: * No isolation of Pseudomonas aeruginosa * No imaging evidence suggestive of osteomyelitis * Patients under 18 years of age
Frequently Asked Questions
Who can join the NCT07056881 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Osteomyelitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07056881 currently recruiting?
Yes, NCT07056881 is actively recruiting participants. Visit ClinicalTrials.gov or contact Centre Hospitalier de Saint-Denis to inquire about joining.
Where is the NCT07056881 trial being conducted?
This trial is being conducted at Saint-Denis, France.
Who is sponsoring the NCT07056881 clinical trial?
NCT07056881 is sponsored by Centre Hospitalier de Saint-Denis. The trial plans to enroll 300 participants.