NCT07323810 Monitoring the Effect of Mental Fatigue on Physical Performance Using Wearable Sensors and Physiological Parameters
| NCT ID | NCT07323810 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Vrije Universiteit Brussel |
| Condition | Mental Fatigue |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-12-03 |
| Primary Completion | 2026-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-12-03 with a primary completion date of 2026-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Mental fatigue (MF) negatively affects both cognitive and physical performance, increasing the risk of errors in high-stakes environments such as sports and surgery. Traditional methods to assess MF rely on subjective self-report scales, which are prone to bias, or on complex brain measurements (e.g. EEG) that are impractical outside laboratory settings. This study aims to develop a real-time, objective monitoring method for MF using wearable physiological sensors. The study will recruit healthy, trained runners (18-35 years old) who will complete both an MF-inducing cognitive task (Stroop test) and a control condition (watching a documentary) in a randomized, counterbalanced, crossover design. Heart rate variability, respiration rate, and pupil metrics will be continuously recorded using wearable devices. Machine learning models will be used to predict MF-level as well as the effect of MF on physical performance (5-km time trial on a treadmill) using the physiological data as input.
Eligibility Criteria
Inclusion Criteria: * Healthy (no neurological, cardiovascular or musculoskeletal disorders of any kind) * Male or female * No prior knowledge of the concept of MF * No medication * Non-smoker * 18-35 years of age * Experienced runners: (≥15km/week and/or ≥2u/week during the last 6 months) Exclusion Criteria: * Injuries in the past 6 months, affecting running performance * Suffering from a chronic health condition (could be neurological, cardiovascular, internal or musculoskeletal) * Participating in any concomitant care or research trials * History of suffering from any mental/psychiatric disorders * Use of medication * Use of caffeine and heavy efforts 24 hours prior each trial * Suffering from colour vision deficiencies * Not eating a standardized meal, the morning of each trial and the evening before each trial
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07323810 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 35 Years, studying Mental Fatigue. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07323810 currently recruiting?
Yes, NCT07323810 is actively recruiting participants. Contact the research team at emilie.schampheleer@vub.be for enrollment information.
Where is the NCT07323810 trial being conducted?
This trial is being conducted at Brussels, Belgium.
Who is sponsoring the NCT07323810 clinical trial?
NCT07323810 is sponsored by Vrije Universiteit Brussel. The trial plans to enroll 30 participants.