NCT06240104 Monitoring of Heart to Guide Myocardial Injury Patients to Wean From Ventilation

Trial Parameters

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Brief Summary

The goal of this prospective randomized controlled clinical trail is to explore the value of integrating continuous cardiac index variability indicators with existing weaning standards to guide perioperative myocardial injury patients weaning. The main question it aims to answer is: whether the introduction of new indicators for weaning standards can improve the success rate of weaning. Treatment that'll be given to participants is: the cardiac index (CI) is continuously monitored from 15-30 minutes prior to the start of the weaning from ventilation. Participants who increase their CI by more than 30% can have their tracheal intubation removed. Researchers will compare the weaning success rate of CI group and control group.

Eligibility Criteria

Inclusion Criteria: * Perioperative myocardial injury patients * Age\>18 years; * Acute Physiology and Chronic Health Evaluation II (APACHEII)\>8 ; * The weaning process has not yet started after surgery; * Expected postoperative cumulative mechanical ventilation time\>24 hours. Exclusion Criteria: * Pregnancy or childbirth less than 42 days; * Patients and their families are unable to cooperate with treatment; * The cumulative actual mechanical ventilation time after surgery is ≤ 24 hours; * Interruption of mechanical ventilation treatment due to death or other reasons before entering the weaning process; * Patients who retain artificial airways after weaning; * Patients who plan to start non-invasive mechanical ventilation treatment immediately after weaning.

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