NCT06342128 Molecular Landscape of Microvascular Inflammation in Kidney Allografts
| NCT ID | NCT06342128 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Paris Translational Research Center for Organ Transplantation |
| Condition | Kidney Rejection Transplant |
| Study Type | OBSERVATIONAL |
| Enrollment | 600 participants |
| Start Date | 2022-01-01 |
| Primary Completion | 2024-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 600 participants in total. It began in 2022-01-01 with a primary completion date of 2024-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Microvascular inflammation in kidney allografts has been widely reappraised in the recent update of Banff classification. There is a critical need to better understand the pathophysiological mechanisms associated with the various phenotypes of microvascular inflammation that are observed in kidney transplants, particularly in order to develop targeted therapeutic approaches.
Eligibility Criteria
Inclusion Criteria: \- Adult kidney transplant recipients, with at least one kidney transplant biopsy performed and assessed according to the international Banff 2022 classification, with or without lesions of microvascular inflammation Exclusion Criteria: * Inadequate biopsy according to the Banff classification * Missing data for Banff lesion scores, donor-specific antibody status, C4d staining * Biopsies showing histological signs of ischemia-reperfusion * Combined transplantation and kidney transplantation after a non-kidney solid organ transplantation
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06342128 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Kidney Rejection Transplant. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06342128 currently recruiting?
Yes, NCT06342128 is actively recruiting participants. Contact the research team at alexandreloupy@inserm.fr for enrollment information.
Where is the NCT06342128 trial being conducted?
This trial is being conducted at Paris, France, Paris, France, Paris, France.
Who is sponsoring the NCT06342128 clinical trial?
NCT06342128 is sponsored by Paris Translational Research Center for Organ Transplantation. The trial plans to enroll 600 participants.
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