Molecular Biology of Polycythemia and Thrombocytosis
Trial Parameters
Brief Summary
Our study is designed to characterize the clinical picture and genetic pattern of Polycythemia and Thrombocytosis. The purpose of this project is to find a gene and its mutation that causes these disorders. When this is accomplished, new therapies to control and eventually cure the disorder can be designed.
Eligibility Criteria
Inclusion Criteria: 1. Subjects with an elevated hemoglobin concentration (\>18 in males and \>16 in females) 2. Subjects with an elevated platelet count (\>450,000) Exclusion Criteria: 1. Subjects who have a known acquired cause of polycythemia and thrombocytosis 2. Subjects with heart disease, left to right heart shunt or severe pulmonary disease