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Recruiting NCT06804265

NCT06804265 Molecular Biology in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections

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Clinical Trial Summary
NCT ID NCT06804265
Status Recruiting
Phase
Sponsor IRCCS Azienda Ospedaliero-Universitaria di Bologna
Condition Periprosthetic Joint Infection (PJI)
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2025-01-07
Primary Completion 2028-04-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2025-01-07 with a primary completion date of 2028-04-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this observational study is to measure the diagnostic accuracy of the Multiplex PCR technique in identifying pathogens during the diagnostic stage of resolving pre-implantation infection, in the context of treatment according to two-stage protocol for PJIs. This evaluation will be conducted by comparing the results obtained by Multiplex PCR with those derived from standard culture examination.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of periprosthetic infection of hip, knee, shoulder on primary or already revised implant. * treatment of infection with two-stage protocol. * Obtaining informed consent * Age ≥18 years Exclusion Criteria: * Isolates obtained during explantation not included in MULTIPLEX PCR panel

Contact & Investigator

Central Contact

Massimiliano De Paolis, MD

✉ massimiliano.depaolis@aosp.bo.it

📞 0512144332

Principal Investigator

Massimiliano - De Paolis, MD

PRINCIPAL INVESTIGATOR

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Frequently Asked Questions

Who can join the NCT06804265 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Periprosthetic Joint Infection (PJI). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06804265 currently recruiting?

Yes, NCT06804265 is actively recruiting participants. Contact the research team at massimiliano.depaolis@aosp.bo.it for enrollment information.

Where is the NCT06804265 trial being conducted?

This trial is being conducted at Bologna, Italy.

Who is sponsoring the NCT06804265 clinical trial?

NCT06804265 is sponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna. The principal investigator is Massimiliano - De Paolis, MD at IRCCS Azienda Ospedaliero-Universitaria di Bologna. The trial plans to enroll 100 participants.

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