NCT07726550 Modified External Oblique Intercostal Plane Block Versus Erector Spinae Plane Block for Open Nephrectomy
| NCT ID | NCT07726550 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Namik Kemal University |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-08-01 |
| Primary Completion | 2027-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-08-01 with a primary completion date of 2027-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective, randomized, assessor-blinded clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Erector Spinae Plane Block (ESPB) and Modified External Oblique Intercostal Plane Block (EOIPB) in patients undergoing elective open nephrectomy under general anesthesia. Sixty adult patients will be randomized to receive either ESPB or EOIPB before surgical incision. All participants will receive standardized general anesthesia and postoperative multimodal analgesia. Postoperative pain scores, opioid consumption, rescue analgesic requirements, and postoperative nausea and vomiting will be assessed during the first 24 hours after surgery. The study aims to determine whether one fascial plane block technique provides superior postoperative pain control and recovery following open nephrectomy.
Eligibility Criteria
Inclusion Criteria: * Age between 18 and 65 years. * American Society of Anesthesiologists (ASA) physical status I or II. * Scheduled for elective open nephrectomy. * Able and willing to provide written informed consent. * Willing to comply with study procedures. Exclusion Criteria: * Refusal to participate or inability to provide informed consent. * Emergency surgery. * Body mass index (BMI) greater than 35 kg/m². * Known allergy or hypersensitivity to local anesthetics. * Infection at the planned block insertion site. * Coagulopathy or ongoing anticoagulant therapy. * Pregnancy or breastfeeding. * Prisoners or other vulnerable populations unable to provide independent consent.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07726550 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07726550 currently recruiting?
Yes, NCT07726550 is actively recruiting participants. Contact the research team at dronurbaran@hotmail.com for enrollment information.
Where is the NCT07726550 trial being conducted?
This trial is being conducted at Tekirdağ, Turkey (Türkiye).
Who is sponsoring the NCT07726550 clinical trial?
NCT07726550 is sponsored by Namik Kemal University. The trial plans to enroll 60 participants.