NCT06275789 Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?
| NCT ID | NCT06275789 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Nova Southeastern University |
| Condition | Alveolar Ridge Preservation |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-01-26 |
| Primary Completion | 2026-06 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared.
Eligibility Criteria
Inclusion Criteria: * Patients in good health * Require the extraction of at least one premolar or molar with future implant placement * Sufficient keratinized gingiva (equal or more than 2mm prior to extraction), * No more than 3mm of buccal bone loss * Flapless extraction possible * Full mouth plaque index of less than 25% Exclusion Criteria: * Nicotine consumption equivalent to or more than 10 cigarettes per day * Electronic cigarette usage * A history of irradiation of head and neck area * Immunodeficiency disease * Uncontrolled systemic health problems (hypertension crisis 180/120, hyperthyroidism, diabetes with HbA1c over 7, recent history of stroke, cancer) History of medications that affect bone remodeling process (bisphosphonates, RANK-L inhibitors) * Previous adverse reaction to the biomaterials used * Pregnancy/lactation, or those who are trying to become pregnant. * Active uncontrolled or untreated periodontal disease * Periapical lesions greater than 1 cm and soft tissue p