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Recruiting NCT05639907

NCT05639907 Miniscrew Stability and Peri-implant Inflammation When Precoated K21 vs Ethanol Control

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Clinical Trial Summary
NCT ID NCT05639907
Status Recruiting
Phase
Sponsor University of Colorado, Denver
Condition Inflammation Caused by the Placement of a Temporary Anchorage Device
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2022-11-11
Primary Completion 2028-06

Eligibility & Interventions

Sex All sexes
Min Age 12 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
K21 Cavity cleanserEthanol control

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 30 participants in total. It began in 2022-11-11 with a primary completion date of 2028-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

To determine if coating miniscrews with K21 would increase the success rate of orthodontic miniscrews by reducing adjacent tissue inflammation.

Eligibility Criteria

Inclusion Criteria: 1. Good general health, with no significant medical findings 2. Requiring at least two miniscrews in their treatment plans (i.e., most participants will have two miniscrews, but some may receive four or six as indicated by their individual treatment plan) 3. Miniscrew pairs indicated with comparable anatomical positions and comparable mechanics (direct vs. indirect anchorage). Exclusion Criteria: 1. Recent or ongoing use of antiresorptive pharmacological agents contraindicating the use of orthodontic miniscrews 2. Less than 12 years of age 3. Heavy tobacco use (\>10 cigarettes/day) 4. Peri-implant tissues must be observable at follow-up appointments 5. Being unable or unwilling to consent to the study

Contact & Investigator

Central Contact

Clifton M Carey, PhD

✉ clifton.carey@cuanschutz.edu

📞 3037241046

Frequently Asked Questions

Who can join the NCT05639907 clinical trial?

This trial is open to participants of all sexes, aged 12 Years or older, studying Inflammation Caused by the Placement of a Temporary Anchorage Device. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05639907 currently recruiting?

Yes, NCT05639907 is actively recruiting participants. Contact the research team at clifton.carey@cuanschutz.edu for enrollment information.

Where is the NCT05639907 trial being conducted?

This trial is being conducted at Aurora, United States.

Who is sponsoring the NCT05639907 clinical trial?

NCT05639907 is sponsored by University of Colorado, Denver. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology