| NCT ID | NCT07021118 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mario Negri Institute for Pharmacological Research |
| Condition | Emergency Departments |
| Study Type | OBSERVATIONAL |
| Enrollment | 2,500 participants |
| Start Date | 2026-01-21 |
| Primary Completion | 2027-01-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 2,500 participants in total. It began in 2026-01-21 with a primary completion date of 2027-01-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Mild TBI is one of the main causes of admission to the Emergency Department (ED). Brain computed tomography (CT) is one of the most widely used diagnostic tools to assess the presence of intracranial lesions. However, in Western countries, 85-95% of CT scans performed in the ED for mild TBI are negative. It is therefore conceivable that a significant number of CTs could be avoided by a more careful use of this exam. On the other hand, excessive use of CT exposes patients to unnecessary radiation, increases healthcare costs and slows down the management of patients in the ED. This study aims to analyze the variability in the use of CT in mild TBI in Italian EDs, validate the scores designed to help the physician decide when to use it and develop a model that predicts the medium-term outcome of patients with mild head trauma.
Eligibility Criteria
Inclusion Criteria: Adult patients arriving in the emergency department. Adult patients with mild TBI Adult patients with Glasgow Coma Scale 13-15. Exclusion Criteria: All patients under 18 years. Patients with trauma-associated loss of consciousness lasting more than 30 minutes. Patients with post-traumatic amnesia lasting more than 24 hours.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07021118 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Emergency Departments. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07021118 currently recruiting?
Yes, NCT07021118 is actively recruiting participants. Contact the research team at giovanni.nattino@marionegri.it for enrollment information.
Where is the NCT07021118 trial being conducted?
This trial is being conducted at Novi Ligure, Italy, Chiari, Italy, Bagno a Ripoli, Italy, Magenta, Italy and 11 additional locations.
Who is sponsoring the NCT07021118 clinical trial?
NCT07021118 is sponsored by Mario Negri Institute for Pharmacological Research. The trial plans to enroll 2,500 participants.