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Recruiting NCT06320899

Mid- or High-flex Rods Versus Low-flex Rods of SpineShape System IV for Treatment of Degenerative Lumbar Spine Diseases

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Plain-language summary for patients

Trial Parameters

Condition Degenerative Lumbar Spinal Stenosis
Sponsor SpineSave AG
Study Type INTERVENTIONAL
Phase N/A
Enrollment 126
Sex ALL
Min Age 18 Years
Max Age 99 Years
Start Date 2024-06-04
Completion 2031-08-31
Interventions
SpineShape System IV straight rod elasticSpineShape System IV straight rod mediumSpineShape System IV straight rod stiff

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Brief Summary

The purpose of this multi-center, randomized, clinical study is to show that the treatment of degenerative lumbar spine with high- or mid-flex rods is not inferior to the treatment with low-flex rods in terms of clinical and safety-related results. The primary aim is to compare the reduction in back pain after the treatment with high- or mid-flex rods with that after treatment with low-flex rods. Secondary, the functionality after treatment with high- or mid-flex rods will be compared to that after treatment with low-flex rods.

Eligibility Criteria

Inclusion Criteria: * degenerative symptoms in 1 to 2 segments in the lumbar spine L1-S1 * signed informed consent of participant * confirmation of the participant that the attendance of follow-up visits are intended * Body-Mass-Index \< 32 * Pedicle screw axis distance \< 30mm * one or more of the following indications: * (dynamic) stenosis in the spinal canal * neuroforaminal stenosis * facet joint syndrome / spondylarthrosis * discopathy (recurrent disc hernia) * degenerative spondylolisthesis (Meyerding \<1) * instability (hypermobility with antelishtesis, hypomobility with retrolisthesis if decompressed) Exclusion Criteria: * missing bone structure, e.g. due to congenital anomalies or sever anatomical deformities that make anchoring of the implant impossible * damaged structural tissue, e.g. due to a bone fracture * application to the thoracic or cervical spine * pronounced idiopathic scoliosis * spondylolisthesis \> Meyerding grad 1 * isthmic spondolylysis * bone tumor * osteocho

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