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Recruiting NCT05975593

NCT05975593 MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial

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Clinical Trial Summary
NCT ID NCT05975593
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Locally Advanced Cervical Carcinoma
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2024-01-11
Primary Completion 2032-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Tumor collection via biopsyBlood collectionDiffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 60 participants in total. It began in 2024-01-11 with a primary completion date of 2032-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after treatment with definitive-intent chemoradiotherapy for patients with locally advanced cervical and pancreatic cancer.

Eligibility Criteria

Inclusion Criteria: * Confirmation of intent to receive radiotherapy for one of the following diagnoses: * Cervical cancer * Pancreatic cancer * ECOG performance status ≤ 2 * At least 18 years old * Able to understand and willing to sign an IRB-approved written informed consent document Exclusion Criteria: * Any issue (medical, anatomic, other) that might preclude safe acquisition of biospecimens at the discretion of the treating physician

Contact & Investigator

Central Contact

Cliff Robinson, M.D.

✉ clifford.robinson@wustl.edu

📞 314-362-8567

Principal Investigator

Cliff Robinson, M.D.

PRINCIPAL INVESTIGATOR

Washington University School of Medicine

Frequently Asked Questions

Who can join the NCT05975593 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Locally Advanced Cervical Carcinoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05975593 currently recruiting?

Yes, NCT05975593 is actively recruiting participants. Contact the research team at clifford.robinson@wustl.edu for enrollment information.

Where is the NCT05975593 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT05975593 clinical trial?

NCT05975593 is sponsored by Washington University School of Medicine. The principal investigator is Cliff Robinson, M.D. at Washington University School of Medicine. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology