NCT05099315 Microbiome in Atopic Dermatitis Under Systemic Therapy
| NCT ID | NCT05099315 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Charite University, Berlin, Germany |
| Condition | Atopic Dermatitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 600 participants |
| Start Date | 2019-10-01 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 600 participants in total. It began in 2019-10-01 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The skin microbiome plays a role in the pathogenesis of atopic dermatitis. However, it is unclear whether the range of microbiota on the skin is the cause or consequence of atopic skin inflammation. The influence of new systemic therapies for the treatment of moderate to severe atopic dermatitis (such as biologics or Janus kinase inhibitors) on the skin microbiome is largely unknown. The main aim of this scientific exploratory study is to investigate whether and how the skin microbiome changes in patients with moderate to severe atopic dermatitis during systemic therapy. This not only allows new hypotheses to be generated on the pathogenesis of atopic dermatitis, but also new objective scales for the severity of atopic dermatitis can be developed.
Eligibility Criteria
Inclusion Criteria: * Patients with moderate to severe atopic dermatitis * Indication for systemic therapy Exclusion Criteria: * Patients under 18 years of age upon introducing systemic therapy * Pregnant and lactating women
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05099315 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Atopic Dermatitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05099315 currently recruiting?
Yes, NCT05099315 is actively recruiting participants. Contact the research team at margitta.worm@charite.de for enrollment information.
Where is the NCT05099315 trial being conducted?
This trial is being conducted at Berlin, Germany.
Who is sponsoring the NCT05099315 clinical trial?
NCT05099315 is sponsored by Charite University, Berlin, Germany. The trial plans to enroll 600 participants.
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