NCT07817498 Microbial Evaluation of MK1 and Clip Attachments in Implant Overdentures
| NCT ID | NCT07817498 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mansoura University |
| Condition | Evaluation of Microbial Colonization Around Implants and Overdenture Surfaces Using MK1 and Clip Attachments |
| Study Type | INTERVENTIONAL |
| Enrollment | 7 participants |
| Start Date | 2026-03-01 |
| Primary Completion | 2026-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 7 participants in total. It began in 2026-03-01 with a primary completion date of 2026-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This crossover clinical trial aims to compare the microbial colonization associated with double-structure bar implant-supported mandibular overdentures retained by either MK1 or conventional clip attachments. Seven completely edentulous patients will receive both attachment systems sequentially, allowing each participant to serve as their own control. Microbial samples will be collected from the intaglio surface of the prosthesis and peri-implant areas at different follow-up intervals to assess the prevalence of oral microorganisms. The findings will help determine whether the type of attachment influences microbial accumulation and may contribute to improved maintenance and long-term success of implant-supported overdentures.
Eligibility Criteria
Inclusion Criteria: * Completely edentulous patients aged 45-65 years. * Medically healthy patients with no systemic conditions affecting implant placement or osseointegration. * Healthy maxillary and mandibular residual ridges covered by firm mucosa. * Adequate mandibular bone volume in the interforaminal region to receive four implants (minimum 4 mm diameter and 12 mm length), confirmed by CBCT. * Class I maxillomandibular relationship with sufficient interarch space for implant-supported overdentures. Exclusion Criteria: * Uncontrolled diabetes mellitus, immune disorders, osteoporosis, or other contraindications to implant therapy. * Parafunctional habits such as bruxism or clenching. * Flabby ridges or oral mucosal diseases. * Severe temporomandibular joint disorders. * History of allergy to denture or implant materials. * Previous radiotherapy to the head and neck region.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07817498 clinical trial?
This trial is open to participants of all sexes, aged 45 Years or older, up to 65 Years, studying Evaluation of Microbial Colonization Around Implants and Overdenture Surfaces Using MK1 and Clip Attachments. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07817498 currently recruiting?
Yes, NCT07817498 is actively recruiting participants. Contact the research team at mohammed.hussein@mans.edu.eg for enrollment information.
Where is the NCT07817498 trial being conducted?
This trial is being conducted at Al Mansurah, Egypt.
Who is sponsoring the NCT07817498 clinical trial?
NCT07817498 is sponsored by Mansoura University. The trial plans to enroll 7 participants.