← Back to Clinical Trials
Recruiting NCT06421103

Micro-dosing Indocyanine Green (ICG) in Children

Trial Parameters

Condition Perfusion
Sponsor Great Ormond Street Hospital for Children NHS Foundation Trust
Study Type INTERVENTIONAL
Phase N/A
Enrollment 90
Sex ALL
Min Age N/A
Max Age 18 Years
Start Date 2024-06
Completion 2028-08
Interventions
Indocyanine Green (ICG)

Brief Summary

The goal of this cohort study is to identify the lowest dose of Indocyanine Green (ICG) that achieves satisfactory intra-operative fluorescence for the assessment of gastrointestinal or genitourinary tract perfusion in children.

Eligibility Criteria

Inclusion Criteria: * Children aged ≤18 years of age * Elective surgery including gastrointestinal or genitourinary tract perfusion assessment Exclusion Criteria: * Renal and liver dysfunction * Active infection * Coagulopathy * Complex congenital heart defect * Previous documented allergy to ICG injection or other iodinated contrast agents * Patients suffering from hyperthyroidism or autonomic thyroid adenomas * Premature infants or neonates in whom exchange transfusion is indicated, due to the hyperbilirubinaemia risk * Concurrent use of sodium bisulphite-containing preparations, such as certain heparin preparations

Related Trials