NCT06421103 Micro-dosing Indocyanine Green (ICG) in Children
| NCT ID | NCT06421103 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Great Ormond Street Hospital for Children NHS Foundation Trust |
| Condition | Perfusion |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2024-06 |
| Primary Completion | 2028-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2024-06 with a primary completion date of 2028-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this cohort study is to identify the lowest dose of Indocyanine Green (ICG) that achieves satisfactory intra-operative fluorescence for the assessment of gastrointestinal or genitourinary tract perfusion in children.
Eligibility Criteria
Inclusion Criteria: * Children aged ≤18 years of age * Elective surgery including gastrointestinal or genitourinary tract perfusion assessment Exclusion Criteria: * Renal and liver dysfunction * Active infection * Coagulopathy * Complex congenital heart defect * Previous documented allergy to ICG injection or other iodinated contrast agents * Patients suffering from hyperthyroidism or autonomic thyroid adenomas * Premature infants or neonates in whom exchange transfusion is indicated, due to the hyperbilirubinaemia risk * Concurrent use of sodium bisulphite-containing preparations, such as certain heparin preparations
Contact & Investigator
Stefano Giuliani
PRINCIPAL INVESTIGATOR
Great Ormond Street Hospital
Frequently Asked Questions
Who can join the NCT06421103 clinical trial?
This trial is open to participants of all sexes, up to 18 Years, studying Perfusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06421103 currently recruiting?
Yes, NCT06421103 is actively recruiting participants. Contact the research team at stefano.giuliani@gosh.nhs.uk for enrollment information.
Where is the NCT06421103 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT06421103 clinical trial?
NCT06421103 is sponsored by Great Ormond Street Hospital for Children NHS Foundation Trust. The principal investigator is Stefano Giuliani at Great Ormond Street Hospital. The trial plans to enroll 90 participants.