NCT06145841 Metagenomic Next-Generation Sequencing Guides Anti-Infection Strategies
| NCT ID | NCT06145841 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Guangzhou 8th People's Hospital |
| Condition | AIDS |
| Study Type | OBSERVATIONAL |
| Enrollment | 400 participants |
| Start Date | 2023-10-23 |
| Primary Completion | 2026-10-23 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 400 participants in total. It began in 2023-10-23 with a primary completion date of 2026-10-23.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to observe the effectiveness of clinical application in guiding anti-infection treatments in AIDS patients with severe pneumonia and/or sepsis using Metagenomic Next-Generation Sequencing-based technology in the real world
Eligibility Criteria
Inclusion Criteria: 1. Confirmed HIV infection; 2. Progression to AIDS stage: CD4+ count \<200 cells/ul and/or occurrence of AIDS opportunistic infections; 3. Age between 18 and 65 years; 4. Meeting the diagnosis of severe pneumonia or septic shock: 1. The criteria for severe pneumonia diagnosis refer to the 2021 ATS (American Thoracic Society) and IDSA (Infectious Diseases Society of America) guidelines for the treatment of community-acquired pneumonia; 2. The criteria for septic shock refer to the Chinese Society of Critical Care Medicine's "Chinese Guidelines for the Emergency Treatment of Sepsis/Septic Shock (2018). Exclusion Criteria: 1. Coexisting central nervous system lesions, severe liver disease, or cirrhosis; 2. Concurrent AIDS-related or unrelated tumors; 3. Women who are pregnant or breastfeeding; 4. Severe underlying diseases of the heart, lungs, liver, kidneys, etc.; 5. Alcohol abuse or drug use; 6. The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial.
Frequently Asked Questions
Who can join the NCT06145841 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying AIDS. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06145841 currently recruiting?
Yes, NCT06145841 is actively recruiting participants. Visit ClinicalTrials.gov or contact Guangzhou 8th People's Hospital to inquire about joining.
Where is the NCT06145841 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT06145841 clinical trial?
NCT06145841 is sponsored by Guangzhou 8th People's Hospital. The trial plans to enroll 400 participants.