Trial Parameters
Brief Summary
Physical activity is a key stimulus for bone metabolism through both direct mechanisms (e.g., as a result of the applied load and/or impact) and indirect mechanisms (e.g., the activation of several metabolic pathways and the production of several mediators and effectors that have systemic effects). However, different kinds of physical activity exert different effects on bone and endocrine system. Aim of the study is to investigate the effects of different kinds of physical activity on bone metabolism and on the relationships existing between bone metabolism, energy metabolism, hormone profile, and organ functionality.
Eligibility Criteria
Inclusion Criteria: * \>/= 18 yo * healthy status * caucasians Exclusion Criteria: * \< 18 yo * pregnancy status * ongoing or previous (\<5 years) neoplasia * acute or chronic inflammatory pathologies * primary metabolic diseases of bone * recent bone fractures (\< 6 months) * chronic drugs * recent drugs administration (\< 2 months) for non steroidal anti-inflammatory drugs (NSAIDs) and steroids * anxious-depressive conditions * inability to understand the information given by the recruiting physician