NCT07183488 Metabolic Effects of Short-Chain Fatty Acids in Healthy Individuals
| NCT ID | NCT07183488 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Copenhagen |
| Condition | Healhty |
| Study Type | INTERVENTIONAL |
| Enrollment | 10 participants |
| Start Date | 2025-09-10 |
| Primary Completion | 2026-02-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 10 participants in total. It began in 2025-09-10 with a primary completion date of 2026-02-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary objective of this study is to investigate the acute physiological and metabolic effects of ingesting the short-chain fatty acids (SCFA)s propionate (three carbon atoms long; C3:0) and butyrate (C4:0) in healthy men and women. This aim will be addressed through a block-randomized cross-over study including two visits with acute intake of propionate and butyrate, respectively. The hypothesis is that plasma ketone body levels will increase during the first three hours after intake of butyrate, but not propionate, in healthy individuals in the overnight fasted state.
Eligibility Criteria
Inclusion Criteria: * Male or female. * Age between 18-40 years old * BMI between 18.5-29 Exclusion Criteria: * Diabetes * Kidney- or liver disease * Pregnant, lactating or planning to become pregnant within the study period * Supplementation with SCFAs * Supplementation with B12 vitamin * Special dietary habits (e.g. vegan/ketogenic diet) * Ongoing cancer treatment * Metabolic or absorptive disorders, gastric bypass operation, or use of medication affecting metabolism or food absorption * Crohn's disease, ulcerative colitis or short bowel syndrome * Inability, physically or mentally, to comply with the procedure required by the study protocol as evaluated by the primary investigator, study manager or clinical responsible
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07183488 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Healhty. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07183488 currently recruiting?
Yes, NCT07183488 is actively recruiting participants. Contact the research team at amalie.sfrederiksen@sund.ku.dk for enrollment information.
Where is the NCT07183488 trial being conducted?
This trial is being conducted at Copenhagen, Denmark.
Who is sponsoring the NCT07183488 clinical trial?
NCT07183488 is sponsored by University of Copenhagen. The trial plans to enroll 10 participants.