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Recruiting NCT06232447

NCT06232447 Menthol, Inflammation, and Nicotine Transition Study

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Clinical Trial Summary
NCT ID NCT06232447
Status Recruiting
Phase
Sponsor Rosalind Franklin University of Medicine and Science
Condition Cigarette Smoking
Study Type INTERVENTIONAL
Enrollment 68 participants
Start Date 2024-03-26
Primary Completion 2027-06

Eligibility & Interventions

Sex All sexes
Min Age 21 Years
Max Age 85 Years
Study Type INTERVENTIONAL
Interventions
Cigarette Type Switching

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 68 participants in total. It began in 2024-03-26 with a primary completion date of 2027-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will focus on examining the potential impact of menthol flavoring in cigarettes on biomarkers of systemic inflammation as a subclinical indicator of cardiovascular disease risk.

Eligibility Criteria

Inclusion criteria * Men and women between 21-85 years old * Currently uses menthol cigarettes * Daily smoking rate of ≥5 cigarettes/day for ≥1 year * Currently own and regularly use an iOS/Android smartphone device able to download the LifeData application * Able to read and communicate fluently in English Exclusion criteria * Currently pregnant or breastfeeding * Actively trying to quit smoking * Current heavy alcohol use * Frequent use of non-menthol cigarettes, other smoking products, or illicit substances * History of severe medical/psychiatric condition or treatment

Contact & Investigator

Central Contact

Nancy C Jao, PhD

✉ nancy.jao@rosalindfranklin.edu

📞 847-578-8747

Principal Investigator

Nancy C Jao, PhD

PRINCIPAL INVESTIGATOR

Rosalind Franklin University of Medicine and Science

Frequently Asked Questions

Who can join the NCT06232447 clinical trial?

This trial is open to participants of all sexes, aged 21 Years or older, up to 85 Years, studying Cigarette Smoking. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06232447 currently recruiting?

Yes, NCT06232447 is actively recruiting participants. Contact the research team at nancy.jao@rosalindfranklin.edu for enrollment information.

Where is the NCT06232447 trial being conducted?

This trial is being conducted at North Chicago, United States.

Who is sponsoring the NCT06232447 clinical trial?

NCT06232447 is sponsored by Rosalind Franklin University of Medicine and Science. The principal investigator is Nancy C Jao, PhD at Rosalind Franklin University of Medicine and Science. The trial plans to enroll 68 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology