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RecruitingNCT04101188

Mechanisms Underlying the Protective Vascular Effects of Dietary Potassium in Humans

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Trial Parameters

ConditionCardiovascular Risk Factor
SponsorUniversity of Delaware
Study TypeINTERVENTIONAL
PhaseN/A
Enrollment90
SexALL
Min Age18 Years
Max Age45 Years
Start Date2020-01-16
Completion2026-07-31
Interventions
Moderate Potassium/Low Sodium DietModerate Potassium/High Sodium DietHigh Potassium/High Sodium Diet

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Brief Summary

Americans continue to consume high amounts of sodium. Potassium is notable for its blood pressure lowering effects but less is known regarding its effect on the vasculature. This investigation seeks to determine the role of dietary potassium on the vasculature in the presence of a high sodium diet in salt-resistant adults.

Eligibility Criteria

Inclusion Criteria: * healthy * normal blood pressure * normal resting ECG Exclusion Criteria: * hypertension * history of heart disease * diabetes * kidney disease * obese (BMI ≥30) * significant weight changes in the last 6 months * use of tobacco products * pregnant * on a special diet (gluten free; vegan) * take any medications for the above conditions * endurance trained athletes

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