NCT06847685 Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
| NCT ID | NCT06847685 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Johns Hopkins University |
| Condition | Endometriosis |
| Study Type | OBSERVATIONAL |
| Enrollment | 140 participants |
| Start Date | 2025-02-01 |
| Primary Completion | 2029-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 140 participants in total. It began in 2025-02-01 with a primary completion date of 2029-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy
Eligibility Criteria
Inclusion Criteria: 1. Subject must be a healthy woman between the ages of 18 and 45 years. 2. Women with diagnosed endometriosis or infertility (cases). 3. Women without a diagnosis of endometriosis or infertility (controls). 4. Subject must have regular menstrual cycles. 5. Subject must have a body mass index (BMI) between 18 and 40. 6. Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum. 7. Subject must be able to understand and provide consent to procedures and use/disclosure of protected health information. 8. No history of Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, hepatitis B, and HIV. 9. For IVF study subjects, a minimum endometrial thickness of 7mm at the time of sample collection. Exclusion Criteria: 1. Pregnant women. 2. Study subjects with endometrial cancer. 3. Study subjects with a history of endometrial ablation. 4. Study subjects with undiagnosed uterine bleeding. 5. Women with reproductive diseases that affect the endometrium (such as fibroids or uterine polyps that distort endometrial cavity). 6. Study subjects with an intrauterine device (IUD).
Contact & Investigator
James Segars, MD
STUDY CHAIR
Johns Hopkins University
Frequently Asked Questions
Who can join the NCT06847685 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 45 Years, studying Endometriosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06847685 currently recruiting?
Yes, NCT06847685 is actively recruiting participants. Contact the research team at jsegars2@jhmi.edu for enrollment information.
Where is the NCT06847685 trial being conducted?
This trial is being conducted at Athens, United States, Baltimore, United States, Piscataway, United States.
Who is sponsoring the NCT06847685 clinical trial?
NCT06847685 is sponsored by Johns Hopkins University. The principal investigator is James Segars, MD at Johns Hopkins University. The trial plans to enroll 140 participants.