NCT03806283 Mechanisms of Pregnancy Vascular Adaptations
| NCT ID | NCT03806283 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Wisconsin, Madison |
| Condition | Pre-Eclampsia |
| Study Type | OBSERVATIONAL |
| Enrollment | 166 participants |
| Start Date | 2018-11-20 |
| Primary Completion | 2027-04 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 166 participants in total. It began in 2018-11-20 with a primary completion date of 2027-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators will collect omental tissue (research surgical excision) and placental tissue (standard of care clinical delivery) from both preeclamptic and non-preeclamptic women during their c-section and use these samples to study the blood vessels, specifically the expression/activation of the AT2R.
Eligibility Criteria
Inclusion Criteria: * Female * Ages 18 to 40 years old * Singleton gestation between 28 weeks, 0 days and 41 weeks, 0 days gestational age at the time of consent * Undergoing caesarean section, either planned or otherwise with or without trial of labor Exclusion Criteria: * Treatment of severe hypertension by antihypertensive or use of magnesium sulfate after the patient is hospitalized for the diagnosis of preeclampsia. * Any major fetal structural anomalies or aneuploidies * Undergoing cesarean section for placental abruption or bleeding complications. * Singleton gestation not within 36 weeks, 0 days and 41 weeks, 0 days gestational age at the time of enrollment (delivery)
Contact & Investigator
Sathish Kumar, PhD
PRINCIPAL INVESTIGATOR
University of Wisconsin, Madison
Frequently Asked Questions
Who can join the NCT03806283 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 40 Years, studying Pre-Eclampsia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03806283 currently recruiting?
Yes, NCT03806283 is actively recruiting participants. Contact the research team at research.crc_obgyn@wisc.edu for enrollment information.
Where is the NCT03806283 trial being conducted?
This trial is being conducted at Madison, United States.
Who is sponsoring the NCT03806283 clinical trial?
NCT03806283 is sponsored by University of Wisconsin, Madison. The principal investigator is Sathish Kumar, PhD at University of Wisconsin, Madison. The trial plans to enroll 166 participants.