NCT06617195 Mechanisms of Anabolic Resistance in Older Humans
| NCT ID | NCT06617195 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Aging |
| Study Type | OBSERVATIONAL |
| Enrollment | 120 participants |
| Start Date | 2025-01-14 |
| Primary Completion | 2028-09-16 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 120 participants in total. It began in 2025-01-14 with a primary completion date of 2028-09-16.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research is to understand how chronic inflammation affects muscle function and responses to exercise in older adults.
Eligibility Criteria
Exclusion Criteria: 1. Diabetes or fasting plasma glucose 126 mg/dL 2. Body mass index (BMI) 30 kg/m2 3. Anemia (female subjects hemoglobin of \<11 g/dl and male subjects hemoglobin \<12 g/dl) 4. Active coronary artery disease or history of unstable macrovascular disease (unstable angina, myocardial infarction, stroke, and revascularization of coronary, peripheral or carotid artery within 3 months of recruitment) 5. Renal failure (serum creatinine \> 1.5mg/dl) 6. Chronic active liver disease (AST\>144IU/L or ALT\>165IU/L) 7. Oral warfarin group medications or history of blood clotting disorders. 8. Smoking 9. Pregnancy or breastfeeding 10. Alcohol consumption greater than 2 glasses/day or other substance abuse 11. Untreated or uncontrolled hypothyroidism 12. Debilitating chronic disease (at the discretion of the investigators)
Contact & Investigator
Ian Lanza
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT06617195 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 85 Years, studying Aging. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06617195 currently recruiting?
Yes, NCT06617195 is actively recruiting participants. Contact the research team at passehl.rachel@mayo.edu for enrollment information.
Where is the NCT06617195 trial being conducted?
This trial is being conducted at Rochester, United States.
Who is sponsoring the NCT06617195 clinical trial?
NCT06617195 is sponsored by Mayo Clinic. The principal investigator is Ian Lanza at Mayo Clinic. The trial plans to enroll 120 participants.