NCT07420946 Mechanical Insufflation-Exsufflation in Critically Ill Patients
| NCT ID | NCT07420946 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medipol University |
| Condition | Airway Clearance |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-06-10 |
| Primary Completion | 2026-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2026-06-10 with a primary completion date of 2026-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases. However, its use in critically ill ICU patients remains inconsistent and lacks standardized guidelines. Despite growing research, current practices vary widely in patient selection, treatment protocols, and safety management, with limited high-quality evidence to support clear recommendations. To address this gap, an international, multidisciplinary Delphi consensus study is needed to establish expert-based best practices and feasible guidelines for the safe and effective implementation of MI-E in the intensive care setting.
Eligibility Criteria
Inclusion Criteria: * Healthcare professionals with documented clinical experience in critical care medicine, pulmonology, anesthesiology, respiratory therapy, or physiotherapy with involvement in airway clearance strategies. * Demonstrated experience or recognized expertise in the clinical use of MI-E, either in critically ill patients or in patients with complex respiratory conditions. * A minimum of 5 years of clinical experience in their respective field, or a proven academic or clinical contribution related to MI-E. * Willingness to participate in multiple Delphi rounds and to provide informed consent. * Ability to complete the questionnaires in English. Exclusion Criteria: * Lack of direct clinical or academic experience related to MI-E or airway clearance techniques. * Inability or unwillingness to provide informed consent. * Failure to complete the first Delphi round after formal invitation and consent. * Withdrawal of consent at any stage of the Delphi process.
Contact & Investigator
Berkan Basançelebi
PRINCIPAL INVESTIGATOR
Medipol University
Frequently Asked Questions
Who can join the NCT07420946 clinical trial?
This trial is open to participants of all sexes, studying Airway Clearance. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07420946 currently recruiting?
Yes, NCT07420946 is actively recruiting participants. Contact the research team at berkan.basancelebi@medipol.edu.tr for enrollment information.
Where is the NCT07420946 trial being conducted?
This trial is being conducted at Naples, Italy, Naples, Italy, Murcia, Spain, Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07420946 clinical trial?
NCT07420946 is sponsored by Medipol University. The principal investigator is Berkan Basançelebi at Medipol University. The trial plans to enroll 30 participants.