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Recruiting NCT06252129

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

Trial Parameters

Condition Lung Cancer
Sponsor Brigham and Women's Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-07-26
Completion 2027-01
Interventions
Subjects undergoing a lung specimen lymph node dissectionControl group

Brief Summary

Lung cancer patients undergoing upfront surgery, highly benefit from a systematic lymph node dissection in the mediastinum and in the surgical specimens. The latter is performed by the pathologist. Developing a standardized technique to dissect the lobectomy specimen has the potential of maximizing the retrieval of all N1 stations lymph nodes. The investigators believe that the adoption of such technique will improve lung cancer staging and identify a higher number of patients that qualify for adjuvant therapies.

Eligibility Criteria

Inclusion Criteria: 1. Subjects with a lung nodule or mass who are eligible to undergo a lobectomy. 2. Subject without any metastasis present. 3. Subjects who have peripheral lung nodule location 4. Subjects must be 18 years of age or older. Exclusion Criteria: 1. Subjects who received preoperative chemotherapy or radiotherapy. 2. Subjects who have a lung nodule located in a central location. Central tumors are defined by those infiltrating the lobar airway.

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