NCT06296186 Massed Prolonged Exposure for PTSD in Substance Use Treatment
| NCT ID | NCT06296186 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Veterans Medical Research Foundation |
| Condition | Stress Disorders, Post-Traumatic |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2024-09-01 |
| Primary Completion | 2028-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2024-09-01 with a primary completion date of 2028-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are: * Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.
Eligibility Criteria
Inclusion Criteria: * Veterans * age 18+ * who have served since September 2001 * who are enrolled in a SUD IOP at a participating VA * meet DSM-5 criteria for a current SUD (Tobacco Use Disorder alone not sufficient for inclusion) * meet DSM-5 criteria for PTSD * report substance use at least 20 of the last 90 days * are able to give informed consent. Exclusion Criteria: * severe cognitive impairment * current suicidal or homicidal intent requiring immediate treatment * current unstable psychotic or manic symptoms not attributable to SUD
Contact & Investigator
Shannon Kehle-Forbes, PhD
PRINCIPAL INVESTIGATOR
University of Minnesota
Frequently Asked Questions
Who can join the NCT06296186 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Stress Disorders, Post-Traumatic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06296186 currently recruiting?
Yes, NCT06296186 is actively recruiting participants. Contact the research team at snorman@ucsd.edu for enrollment information.
Where is the NCT06296186 trial being conducted?
This trial is being conducted at San Diego, United States, Tampa, United States, Atlanta, United States, Chicago, United States and 2 additional locations.
Who is sponsoring the NCT06296186 clinical trial?
NCT06296186 is sponsored by Veterans Medical Research Foundation. The principal investigator is Shannon Kehle-Forbes, PhD at University of Minnesota. The trial plans to enroll 200 participants.