NCT06988111 Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)
| NCT ID | NCT06988111 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Assiut University |
| Condition | Respiratory Failure Without Hypercapnia |
| Study Type | INTERVENTIONAL |
| Enrollment | 180 participants |
| Start Date | 2025-07-01 |
| Primary Completion | 2026-07-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 180 participants in total. It began in 2025-07-01 with a primary completion date of 2026-07-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.
Eligibility Criteria
Inclusion criteria: * Age above 18 years * within 48 hours after major surgery * PAO2/FIO2 less than 200 * Signs of respiratory distress and respiratory rate (RR) more than 25 cycles/minute Exclusion Criteria: * Age below 18 years * Pregnant ladies * Orofacial trauma or burns * Active Gastrointestinal bleeding
Contact & Investigator
Ahmad M. Shaddad, MD
PRINCIPAL INVESTIGATOR
Assuit Univeristy
Frequently Asked Questions
Who can join the NCT06988111 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Respiratory Failure Without Hypercapnia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06988111 currently recruiting?
Yes, NCT06988111 is actively recruiting participants. Contact the research team at shaddad_ahmad@aun.edu.eg for enrollment information.
Where is the NCT06988111 trial being conducted?
This trial is being conducted at Asyut, Egypt.
Who is sponsoring the NCT06988111 clinical trial?
NCT06988111 is sponsored by Assiut University. The principal investigator is Ahmad M. Shaddad, MD at Assuit Univeristy. The trial plans to enroll 180 participants.