NCT00181259 Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
| NCT ID | NCT00181259 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Johns Hopkins University |
| Condition | Heart Failure, Congestive |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 1988-01 |
| Primary Completion | 2027-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 1988-01 with a primary completion date of 2027-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart failure and whether that contributes to the poor heart function.
Eligibility Criteria
Inclusion Criteria: * age \> 18 years * Healthy subjects: no history of heart disease * Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) \<40% * Left ventricular hypertrophy: wall thickness \>1.2cm * Coronary artery disease: \>50% coronary lesion or positive stress test Exclusion Criteria: * contraindication to MRI
Contact & Investigator
Robert G. Weiss, MD
PRINCIPAL INVESTIGATOR
Johns Hopkins University
Frequently Asked Questions
Who can join the NCT00181259 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Heart Failure, Congestive. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT00181259 currently recruiting?
Yes, NCT00181259 is actively recruiting participants. Contact the research team at rweiss@jhmi.edu for enrollment information.
Where is the NCT00181259 trial being conducted?
This trial is being conducted at Baltimore, United States.
Who is sponsoring the NCT00181259 clinical trial?
NCT00181259 is sponsored by Johns Hopkins University. The principal investigator is Robert G. Weiss, MD at Johns Hopkins University. The trial plans to enroll 500 participants.
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