NCT07486219 Magnetic Resonance Imaging of the Lung: Oncological Applications
| NCT ID | NCT07486219 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia |
| Condition | Lung Cancer (NSCLC) |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2020-01-15 |
| Primary Completion | 2026-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2020-01-15 with a primary completion date of 2026-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Lung neoplasms are characterized by a complex interaction between tumor cells and a variety of resident and infiltrating host elements, secreted factors, and extracellular matrix proteins, collectively referred to as the microenvironment. Nowadays, in the setting of lung cancer, and in particular non-small cell lung cancer (NSCLC), the evaluation of microenvironment characteristics can only be performed by a pathologist and only on histological material. By combining different MRI parameters, it may be possible to create a specific imaging "signature" for the three different immune phenotypes and thus be able to make a distinction based on MRI examination.
Eligibility Criteria
Inclusion Criteria: * Primary NSCLC of the lung (TNM 8th edition T parameter ≥T1c) * Biopsy examination of the primary tumor adequate at least for PDL-1 quantification * Staging CT scan with uncertain N parameter and definite M parameter. Exclusion Criteria: * Absolute contraindications to magnetic resonance imaging or the administration of gadolinium-based contrast agents
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07486219 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Lung Cancer (NSCLC). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07486219 currently recruiting?
Yes, NCT07486219 is actively recruiting participants. Contact the research team at c.bortolotto@smatteo.pv.it for enrollment information.
Where is the NCT07486219 trial being conducted?
This trial is being conducted at Pavia, Italy.
Who is sponsoring the NCT07486219 clinical trial?
NCT07486219 is sponsored by Fondazione IRCCS Policlinico San Matteo di Pavia. The trial plans to enroll 50 participants.
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