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Recruiting NCT04498221

NCT04498221 Lymphatic Mapping Of Oropharyngeal Cancer

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Clinical Trial Summary
NCT ID NCT04498221
Status Recruiting
Phase
Sponsor University College, London
Condition Oropharyngeal Cancer
Study Type INTERVENTIONAL
Enrollment 150 participants
Start Date 2022-07-07
Primary Completion 2027-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Imaging procedureSurgical procedure

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 150 participants in total. It began in 2022-07-07 with a primary completion date of 2027-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

A multi-centre validation study to evaluate whether a new imaging and surgical protocol would work as well as the current gold standard in identifying sentinel nodes in patients with oropharyngeal cancer.

Eligibility Criteria

Inclusion Criteria: * Adults aged 18 or over * New diagnosis of OPC - all anatomical subsites and HPV status accepted * Unilateral metastatic nodes equating to AJCC TNM8 clinical staging N1-N2b for P16 negative and N1 for P16 positive patients. Exclusion Criteria: * Suspicious bilateral nodes on imaging * Previous radiotherapy or surgery to the neck * Second primary oropharyngeal tumours * Distant metastasis (e.g. lung, bone) * Pregnancy and lactation * Inability to give informed consent * Allergy to lymphatic tracers

Contact & Investigator

Central Contact

Trial Manager

✉ ncita.looc@ucl.ac.uk

📞 02076799274

Principal Investigator

Clare Schilling

PRINCIPAL INVESTIGATOR

University College, London

Frequently Asked Questions

Who can join the NCT04498221 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Oropharyngeal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04498221 currently recruiting?

Yes, NCT04498221 is actively recruiting participants. Contact the research team at ncita.looc@ucl.ac.uk for enrollment information.

Where is the NCT04498221 trial being conducted?

This trial is being conducted at London, United Kingdom, London, United Kingdom.

Who is sponsoring the NCT04498221 clinical trial?

NCT04498221 is sponsored by University College, London. The principal investigator is Clare Schilling at University College, London. The trial plans to enroll 150 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology