NCT07261956 Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia
| NCT ID | NCT07261956 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Saint Thomas Hospital, Panama |
| Condition | Pulmonary Edema - Acute |
| Study Type | INTERVENTIONAL |
| Enrollment | 202 participants |
| Start Date | 2025-08-25 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 202 participants in total. It began in 2025-08-25 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery. The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented. Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels. The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.
Eligibility Criteria
Inclusion Criteria: * Preeclampsia with severe features. * Gestational age 24 weeks - 41 weeks. Exclusion Criteria: * Chronic lung disease. * Known heart disease. * Diagnosis of lung edema at admission * Body mass index \> 40 * Need for immediate delivery
Contact & Investigator
Osvaldo Reyes, MD
STUDY DIRECTOR
Saint Thomas Hospital, Panama
Frequently Asked Questions
Who can join the NCT07261956 clinical trial?
This trial is open to female participants only, studying Pulmonary Edema - Acute. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07261956 currently recruiting?
Yes, NCT07261956 is actively recruiting participants. Contact the research team at annacfigue@gmail.com for enrollment information.
Where is the NCT07261956 trial being conducted?
This trial is being conducted at Panama City, Panama.
Who is sponsoring the NCT07261956 clinical trial?
NCT07261956 is sponsored by Saint Thomas Hospital, Panama. The principal investigator is Osvaldo Reyes, MD at Saint Thomas Hospital, Panama. The trial plans to enroll 202 participants.