NCT07044089 Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery
| NCT ID | NCT07044089 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kocaeli University |
| Condition | Peep Titration in Lung Protective Ventilation |
| Study Type | OBSERVATIONAL |
| Enrollment | 86 participants |
| Start Date | 2025-07-23 |
| Primary Completion | 2027-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 86 participants in total. It began in 2025-07-23 with a primary completion date of 2027-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery. Researcher aimed to compare the effects of two different PEEP application methods on intraoperative hemodynamics, respiratory mechanics, and gas exchange, as well as postoperative extubation times, respiratory complications (atelectasis, need for non invasive mechanical ventilatıon, need for re-entubatıon) length of stay in the intensive care unit, and discharge times.
Eligibility Criteria
Inclusion Criteria: * Patients scheduled for elective on-pump coronary artery bypass graft surgery via median sternotomy * Patients between the ages of 18 and 70 * ASA (American Society of Anesthesiologists) physical status classification II-III Exclusion Criteria: * Patients with an ejection fraction below 35% * Patients who did not consent to participate in the study * Patients undergoing emergency surgery * Patients who are allergic to the anesthetic drugs used * Patients who have undergone lung resection * Those with a history of mechanical ventilation in the 2 months before surgery * Patients who have undergone total circulatory arrest and deep hypothermia * Patients with obstructive sleep apnea syndrome requiring long-term ventilation assistance * Morbid obesity (Body Mass Index\>35kg/m2) * Patients with refractory hypoxemia (arterial oxygen saturation below 88% despite 100% oxygen inhalation) * COPD (FEV1\<70%) * Patients with chronic renal failure (serum creatine\>1.8 mg/dl) * Anemia (Hg\<10 gr/dl) * Patients who have had an intraaortic balloon pump placed.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07044089 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Peep Titration in Lung Protective Ventilation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07044089 currently recruiting?
Yes, NCT07044089 is actively recruiting participants. Contact the research team at zeynebacik96@gmail.com for enrollment information.
Where is the NCT07044089 trial being conducted?
This trial is being conducted at Kocaeli, Turkey (Türkiye).
Who is sponsoring the NCT07044089 clinical trial?
NCT07044089 is sponsored by Kocaeli University. The trial plans to enroll 86 participants.