NCT07641413 Lung and Heart Function Across Decades of Life in Health
| NCT ID | NCT07641413 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, San Francisco |
| Condition | Pollution Related Respiratory Disorder |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2024-08-01 |
| Primary Completion | 2030-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2024-08-01 with a primary completion date of 2030-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main objective of this study is to develop baseline "normal" reference values of both lung and heart function for healthy adults within the age range relevant to the United States Veteran population who served in the Southwest Asia theater of military operations. This study will involve performing key components of the Department of Veterans Affairs the Airborne Hazards and Open Burn Pit Center of Excellence (AHOBPCE) and a VA network of Post-Deployment Cardiopulmonary Evaluation Network (PDCEN) Core Clinical Evaluation in asymptomatic unexposed healthy controls without known lung or heart disease to serve as a "normal" control comparator group for veterans evaluated by PDCEN.
Eligibility Criteria
Inclusion Criteria: * Age 24-68 * No respiratory complaints (defined as modified Medical Research Council score = 0) * No use of respiratory medications Exclusion Criteria: * Non-English speaking * Pregnancy * BMI\>35 Kg/m2 * Tobacco smoking within prior year * Lifetime tobacco smoking of \>5 pack-years * Current inhaled cannabis use (any modality) \>2x weekly * Prior inhaled cannabis uses exceeding 2x weekly within the prior year * Illicit drug use (other than cannabis) * No prior or current major organ disease, including but not limited to: * Neuromuscular weakness * History of malignancy (other than non-melanoma skin cancer)-- HIV/AIDS * Autoimmune disease * Solid-organ or hematopoietic stem cell transplant * Cardiovascular disease (other than mild HTN; \< 140/90; controlled on 2 or less medications) * Poorly-controlled HTN (SBP\>140 or DBP\>90 or use of more than 2 anti-hypertensive medications) * Any history of congestive heart failure (CHF, either HFpEF or HFrEF) * Any history of arrythmia (including atrial fibrillation)
Contact & Investigator
Mehrdad Arjomandi, MD
PRINCIPAL INVESTIGATOR
University of California, San Francisco
Frequently Asked Questions
Who can join the NCT07641413 clinical trial?
This trial is open to participants of all sexes, aged 24 Years or older, up to 68 Years, studying Pollution Related Respiratory Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07641413 currently recruiting?
Yes, NCT07641413 is actively recruiting participants. Contact the research team at mehrdad.arjomandi@ucsf.edu for enrollment information.
Where is the NCT07641413 trial being conducted?
This trial is being conducted at San Francisco, United States.
Who is sponsoring the NCT07641413 clinical trial?
NCT07641413 is sponsored by University of California, San Francisco. The principal investigator is Mehrdad Arjomandi, MD at University of California, San Francisco. The trial plans to enroll 200 participants.