| NCT ID | NCT04142606 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Condition | Pregnancy |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,500 participants |
| Start Date | 2019-12-06 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,500 participants in total. It began in 2019-12-06 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Congenital anomalies are a major public health problem. They affect 2-3% of births, around 20,000 new cases per year in France, of which 15% are cared for in Ile de France. These congenital anomalies are a major cause of morbidity, infant mortality and disability. They are also a major cause of death during the infant period (22% of deaths during the first year of life: source CépiDC Inserm 2010). The detection, accurate diagnosis and accurate prognosis, particularly functional, of these congenital anomalies are still difficult in the current monitoring of pregnancy, which is based primarily on ultrasound. The use and development of modern imaging techniques is now essential to enable doctors to better see and better examine the fetus. Alongside ultrasound, Magnetic Resonance Imaging (MRI) is a technique that has undergone significant development in recent years. MRI must allow the effective anatomical and functional evaluation of the main fetal organs and could in particular be interesting in several situations in which it has not yet been sufficiently evaluated and is not yet performed in clinical routine.
Eligibility Criteria
Inclusion Criteria: * patient ≥ 18 years * Single or twin pregnancy * gestational age≥ 16 WG and ≤ 36 WG based on cranio-caudal length (LCC) dating * Collection of the patient's consent Exclusion Criteria: contraindication to MRI * multiple pregnancies \> 2 * subsequent follow-up impossible * maternal condition contraindicates continuation of pregnancy * patient having to have an MRI examination as part of the normal clinical follow-up of her pregnancy (identified or strongly suspected echocardiographic abnormality on ultrasound, diaphragmatic dome hernia, CMV fetal infection, antecedent brain abnormality in siblings, STT operated)
Contact & Investigator
Laurent Salomon, MD, PhD
PRINCIPAL INVESTIGATOR
Assistance Publique - Hôpitaux de Paris
Frequently Asked Questions
Who can join the NCT04142606 clinical trial?
This trial is open to female participants only, aged 18 Years or older, studying Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04142606 currently recruiting?
Yes, NCT04142606 is actively recruiting participants. Contact the research team at david.grevent@gmail.com for enrollment information.
Where is the NCT04142606 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT04142606 clinical trial?
NCT04142606 is sponsored by Assistance Publique - Hôpitaux de Paris. The principal investigator is Laurent Salomon, MD, PhD at Assistance Publique - Hôpitaux de Paris. The trial plans to enroll 1,500 participants.