NCT03065231 Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage
| NCT ID | NCT03065231 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, San Diego |
| Condition | Vasospasm, Intracranial |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2017-01-01 |
| Primary Completion | 2027-01-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2017-01-01 with a primary completion date of 2027-01-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Vasospasm is a common complication after rupture of intracranial aneurysms causing devastating neurologic deficits and death. Vasospasm has been directly associated with the amount of subarachnoid blood inside the basal cisterns. Prior literature has attempted to refine treatment of ruptured intracranial aneurysms but does not have clear guidelines on the optimal method to drain subarachnoid blood. Two methods, extraventricular drain (EVD) and lumbar drain (LD) have been compared retrospectively yet remain controversial as to which method is optimal in reducing subarachnoid blood and preventing vasospasm. This study would be a prospective randomized trial in which patients would be assigned to EVD or LD and observed to see if one method of intervention is associated with preventing clinical vasospasm, decreasing subarachnoid blood, shortening overall ICU stay, and reducing the need for a permanent ventriculoperitoneal shunt. The conclusions of this study may identify an optimal treatment modality to benefit all future patients with ruptured intracranial aneurysms.
Eligibility Criteria
Inclusion Criteria: * patients received at the UCSD Medical Center with grade II, III, IV subarachnoid hemorrhage or patients with aneurysmal SAH with radiographic evidence. Exclusion Criteria: * patients under the age of 18, excluding minors from this study
Frequently Asked Questions
Who can join the NCT03065231 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 110 Years, studying Vasospasm, Intracranial. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03065231 currently recruiting?
Yes, NCT03065231 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of California, San Diego to inquire about joining.
Where is the NCT03065231 trial being conducted?
This trial is being conducted at San Diego, United States.
Who is sponsoring the NCT03065231 clinical trial?
NCT03065231 is sponsored by University of California, San Diego. The trial plans to enroll 100 participants.