NCT07645027 Low Volume Nose Resistance Breathing Exercise With Incentive Spirometer in Patient With Cervical Spinal Cord Injuries
| NCT ID | NCT07645027 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Riphah International University |
| Condition | Cervical Spinal Cord Injury |
| Study Type | INTERVENTIONAL |
| Enrollment | 42 participants |
| Start Date | 2026-05-01 |
| Primary Completion | 2026-08-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 42 participants in total. It began in 2026-05-01 with a primary completion date of 2026-08-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized clinical trial aims to evaluate the effectiveness of combining Low Volume Nose Resistance Breathing Exercises (LVNRBE) with Incentive Spirometry (IS) on respiratory outcomes in patients with cervical spinal cord injury (SCI). Respiratory complications are a major concern in cervical SCI due to impaired respiratory muscle function, leading to reduced lung volumes, dyspnea, ineffective cough, and sputum retention. The study will recruit 42 inpatients aged 18-38 years with cervical SCI (C4-C7), randomly divided into two groups: Data Analysis: Statistical tests (paired and independent t-tests) will determine intra- and intergroup differences using SPSS v25, with significance set at p \< 0.05. * Group A (Intervention): Receives LVNRBE using an Acapella device plus IS for 20 minutes, three times daily, five days a week for four weeks. * Group B (Control): Receives conventional respiratory physiotherapy with the same frequency and duration. Outcomes will be assessed pre- and post-intervention using: * Pulmonary Function Tests (FVC, FEV1), * Modified Borg Dyspnea Scale, * Cough Frequency Scale, * Sputum Grading Scale.
Eligibility Criteria
Inclusion Criteria: * Diagonosed cervical spine injury C4-C7 * Age 18-38 years * Undergoing in-patient rehabilitation * No previous history of severe pulmonary disease * Disease duration \<1 year * Ability to give informed consent * Road Accident Exclusion Criteria: * Uncontrolled hypertension * Other Neuromuscular disease * Stage 3-4 pressure wound * Clinical instability * Traumatic Brain injury
Contact & Investigator
Arjumand Bano, MS
PRINCIPAL INVESTIGATOR
Riphah International University
Frequently Asked Questions
Who can join the NCT07645027 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 38 Years, studying Cervical Spinal Cord Injury. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07645027 currently recruiting?
Yes, NCT07645027 is actively recruiting participants. Contact the research team at iqbal.tariq@riphah.edu.pk for enrollment information.
Where is the NCT07645027 trial being conducted?
This trial is being conducted at Lahore, Pakistan.
Who is sponsoring the NCT07645027 clinical trial?
NCT07645027 is sponsored by Riphah International University. The principal investigator is Arjumand Bano, MS at Riphah International University. The trial plans to enroll 42 participants.