NCT06877312 Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
| NCT ID | NCT06877312 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Manitoba |
| Condition | Dementia; Degenerative, Dementia Mixed |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2024-10-09 |
| Primary Completion | 2030-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2024-10-09 with a primary completion date of 2030-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.
Eligibility Criteria
Inclusion Criteria: * ability to read, write and speak English fluently * MoCA score between 5 and 24 Exclusion Criteria: * Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder. * Having a history of epileptic seizures or epilepsy * Inability to adequately communicate in English * Impaired vision or hearing severe enough to impair performance in cognitive tests * Current substance abuse disorder * Currently participating in another therapeutic study for dementia * Plan to change the medication during any treatment period (5 weeks including the pre-post assessments)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06877312 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 95 Years, studying Dementia; Degenerative, Dementia Mixed. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06877312 currently recruiting?
Yes, NCT06877312 is actively recruiting participants. Contact the research team at Shelly.rempelrossum@umanitoba.ca for enrollment information.
Where is the NCT06877312 trial being conducted?
This trial is being conducted at Winnipeg, Canada.
Who is sponsoring the NCT06877312 clinical trial?
NCT06877312 is sponsored by University of Manitoba. The trial plans to enroll 200 participants.