Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
Trial Parameters
Brief Summary
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.
Eligibility Criteria
Inclusion Criteria: * ability to read, write and speak English fluently * MoCA score between 5 and 24 Exclusion Criteria: * Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder. * Having a history of epileptic seizures or epilepsy * Inability to adequately communicate in English * Impaired vision or hearing severe enough to impair performance in cognitive tests * Current substance abuse disorder * Currently participating in another therapeutic study for dementia * Plan to change the medication during any treatment period (5 weeks including the pre-post assessments)