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Recruiting NCT05024175

NCT05024175 Long-term Follow-up of Subjects Treated With CAR T Cells

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Clinical Trial Summary
NCT ID NCT05024175
Status Recruiting
Phase
Sponsor Marcela V. Maus, M.D.,Ph.D.
Condition Long Term Adverse Effects
Study Type OBSERVATIONAL
Enrollment 45 participants
Start Date 2023-08-07
Primary Completion 2038-08-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Disease assessmentsTumor BiopsyBlood test

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 45 participants in total. It began in 2023-08-07 with a primary completion date of 2038-08-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a single site, non-randomized, open-label, long-term safety and efficacy follow-up study for Phase 1 studies that evaluate the safety and efficacy of CAR T cells: NCT05660369 (DF/HCC# 22-175) and NCT06026319 (DF/HCC# 23-474).

Eligibility Criteria

Inclusion Criteria: Subjects will be asked to participate leading up to the last DF/HCC corresponding main study visit. Subjects meeting the following criteria are eligible for study participation: * Provision of voluntary written informed consent by subject * CAR T cells were administered in DF/HCC IRB corresponding main study Exclusion Criteria: Subjects meeting the following criterion are to be excluded from study participation: \- Subject unable to comply with study requirements

Contact & Investigator

Central Contact

Matthew J Frigault, MD

✉ mfrigault@mgb.org

📞 617-643-6175

Principal Investigator

Matthew J Frigault, MD

PRINCIPAL INVESTIGATOR

Massachusetts General Hospital

Frequently Asked Questions

Who can join the NCT05024175 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Long Term Adverse Effects. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05024175 currently recruiting?

Yes, NCT05024175 is actively recruiting participants. Contact the research team at mfrigault@mgb.org for enrollment information.

Where is the NCT05024175 trial being conducted?

This trial is being conducted at Boston, United States.

Who is sponsoring the NCT05024175 clinical trial?

NCT05024175 is sponsored by Marcela V. Maus, M.D.,Ph.D.. The principal investigator is Matthew J Frigault, MD at Massachusetts General Hospital. The trial plans to enroll 45 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology